Codeine phosphate in paediatric medicine

Codeine phosphate in paediatric medicine.

Codeine is an old drug that still enjoys widespread clinical use although the logical basis for its popularity has been questioned. It is considered to be suitable for mild to moderate pain but not for more intense pain even in large doses. The World Health Organisation has devised a three-step analgesic ladder for the progressive treatment of increasing pain; on this codeine is considered a we...

Codeine phosphate hemihydrate manufacturers in India, cas. No. 41444-62-6, Active Pharmaceuticals Ingredients Codeine phosphate hemihydrate, API Manufacturer, Codeine phosphate hemihydrate buy, sell, import, export,

PAGE-1 Taj Pharma Group Active Pharmaceuticals Ingredients Fine Chemicals Codeine phosphate hemihydrate manufacturers in India, cas. No. 41444-62-6, Active Pharmaceuticals Ingredients Codeine phosphate hemihydrate, API Manufacturer, Codeine phosphate hemihydrate buy, sell, import, export, manufacturing, export Codeine phosphate hemihydrate, trading, India, Codeine phosphate hemihydrate API Manu...

Hypoxaemia and hypotension after intravenous codeine phosphate.

This report describes a case of accidental intravenous administration of codeine phosphate (1 mg.kg-1) to a previously healthy five-year-old boy, who was undergoing strabismus surgery. Hypoxaemia (SpO2 85% with FIO2 of 1) and hypotension (systolic BP 65 mmHg) resulted, which responded to resuscitation with lactated Ringers' (20 ml.kg-1) and phenylephrine (2 micrograms.kg-1). The degree of hypox...

Codeine phosphate in children: time for re-evaluation?

Proposal for deletion Codeine phosphate tablets for pain in children

Codeine is a phenanthrene opioid derivative. It is listed in the 2010 WHO Model List of Essential Medicines for Children and in the 2010 WHO Model Formulary for Children to be used as analgesic for pain relief. Codeine phosphate has been recommended and widely used for the relief of moderate pain in children. WHO has undertaken the update of the 1998 WHO Guidelines on Cancer Pain Relief and Pal...